Background: Early establishment of energy balance related behaviors (EBRBs) may be effective in combating unhealthy lifestyle in preschoolers. Parents are responsible for cultivating preschoolers' EBRBs directly through parenting practices. Although investigating the impact of various parenting practices on preschoolers' EBRBs is crucial to determine which practices should be recommended to parents to help reverse childhood unhealthy lifestyle, it is important to assess whether these effects of parenting practices on preschoolers' EBRBs would be similar across different groups of preschoolers, necessitating research into the moderating effects of demographic characteristics.
View Article and Find Full Text PDFMost genetic risk variants linked to ocular diseases are non-protein coding and presumably contribute to disease through dysregulation of gene expression, however, deeper understanding of their mechanisms of action has been impeded by an incomplete annotation of the transcriptional regulatory elements across different retinal cell types. To address this knowledge gap, we carried out single-cell multiomics assays to investigate gene expression, chromatin accessibility, DNA methylome and 3D chromatin architecture in human retina, macula, and retinal pigment epithelium (RPE)/choroid. We identified 420,824 unique candidate regulatory elements and characterized their chromatin states in 23 sub-classes of retinal cells.
View Article and Find Full Text PDFMicrobiol Resour Announc
December 2024
Here, we present amplicon sequences from sourdough starter cultures that have been treated with a chlorine concentration gradient mirroring public water distribution systems. Data derived present insights into the effect of important environmental factors that may influence the formation of microbial communities in food biomes.
View Article and Find Full Text PDFJ Obes Metab Syndr
December 2024
Weightism, also known as weight-related discrimination, is pervasive and believed to be one of the socially accepted types of discrimination in Asia. Weightism is pervasive, impactful, and has significant repercussions on individuals grappling with excess weight. Despite being a major risk factor for obesity, excess weight is not well documented in the Asian literature.
View Article and Find Full Text PDFAs the prevalence of childhood obesity continues to rise, there is an increase in demand for temporary and minimally invasive alternatives to bariatric surgery as solutions for addressing pediatric obesity. Intragastric balloon (IGB) placement is an increasingly popular methodology for addressing adult obesity; however, it is not approved for the pediatric population. We describe the case of a 17-year-old adolescent female who underwent IGB placement in Colombia and failed to receive proper follow-up care in the country of insertion resulting in a gastric outlet obstruction.
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