Health-related social control in overweight romantic couples: daily associations with physical activity and affect for targets and agents.

Background: Physical activity is essential for health and wellbeing. However, many individuals fail to reach the recommended levels and obesity rates are increasing. Health-related social control refers to strategies employed by 1 person (agent) to influence another person's (target) health behavior.

Effectiveness of Neighborhood Care Volunteer Training Programs: A Mixed-Methods Study.

Objective: To develop and implement a tiered training model for neighborhood caregiving volunteers and to evaluate its impact on participants' knowledge, behaviors, and attitudes toward caregiving services.

Design And Methods: We employed a mixed-methods research design. Participants included 32 neighborhood care volunteers and six seed volunteers.

Factors influencing the decision to receive total knee replacement among patients with severe knee osteoarthritis under universal health insurance coverage.

This study aimed to investigate the factors influencing the decision of patients with severe knee osteoarthritis, who are covered by universal health insurance, to undergo total knee replacement (TKR) surgery, as recommended by orthopedic physicians. A questionnaire survey was used to collect participants' demographics, socio-economic status, medical history, baseline Oxford Knee Score (OKS), and EuroQol-5 Dimension Questionnaire (EQ-5D). We included 704 patients with severe knee osteoarthritis, of which 487 underwent TKR (surgery group), while 217 did not (non-surgery group).

Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways.

Targeting neutrophil function has gained attention as a propitious therapeutic strategy for diverse inflammatory diseases. Accordingly, a series of enone-based derivatives were developed to inhibit neutrophil-mediated inflammation, showing promise for treating inflammatory diseases. These compounds fall into two clusters with distinct effects: one inhibits neutrophilic superoxide (SO) anion production and elastase release triggered by N-formyl-Met-Leu-Phe (fMLF), with compound being most effective (IC values of 1.