Publications by authors named "P C Gottschalk"
Silicone tubing is a frequently used material in pharmaceutical filling processes for parenteral formulations, as its characteristics like flexibility, chemical resistance and easy handling make it particularly suitable for these purposes. This study investigated the time-dependent interaction of phenol and m-cresol with silicone tubing and other broadly applied contact materials used during the filling and transport processes of parenteral formulations. Phenol losses could be observed after incubation in silicone tubing, depending on the inner diameter (ID).
View Article and Find Full Text PDFArticle Synopsis
- - Wetlands are significant sources of methane (CH4) but add uncertainty to global CH4 budgets due to complex controls on its dynamics; this study explores how various environmental predictors influence methane flux across different wetland types over various time scales.
- - Key environmental factors affecting methane flux include soil and air temperatures and water table depth (WTD), with findings showing that changes in methane emissions can lag behind fluctuations in these variables by several days.
- - The study utilizes various statistical methods to highlight that both physical processes, like evaporation, and biological factors, such as photosynthesis, play crucial roles in methane release, enhancing the understanding of wetland methane dynamics.
The impact of occasional drought periods on vegetation spread and greenhouse gas exchange in rewetted fens.
Philos Trans R Soc Lond B Biol Sci
October 2020
Peatland rewetting aims at stopping the emissions of carbon dioxide (CO) and establishing net carbon sinks. However, in times of global warming, restoration projects must increasingly deal with extreme events such as drought periods. Here, we evaluate the effect of the European summer drought 2018 on vegetation development and the exchange of methane (CH) and CO in two rewetted minerotrophic fens (Hütelmoor-Hte and Zarnekow-Zrk) including potential carry-over effects in the post-drought year.
View Article and Find Full Text PDFAltered energy partitioning across terrestrial ecosystems in the European drought year 2018.
Philos Trans R Soc Lond B Biol Sci
October 2020
Drought and heat events, such as the 2018 European drought, interact with the exchange of energy between the land surface and the atmosphere, potentially affecting albedo, sensible and latent heat fluxes, as well as CO exchange. Each of these quantities may aggravate or mitigate the drought, heat, their side effects on productivity, water scarcity and global warming. We used measurements of 56 eddy covariance sites across Europe to examine the response of fluxes to extreme drought prevailing most of the year 2018 and how the response differed across various ecosystem types (forests, grasslands, croplands and peatlands).
View Article and Find Full Text PDFMyositis-Specific Antibodies and Myositis-Associated Antibodies in Patients With Idiopathic Inflammatory Myopathies From the PANLAR Myositis Study Group.
J Clin Rheumatol
December 2021
Background: Dermatomyositis (DM) and polymyositis (PM) are forms of idiopathic inflammatory myopathies (IIMs), which are associated with the production of autoantibodies that are useful in the diagnosis and prognosis of the disease.
Objective: The aim of this study was to determine the frequency of antinuclear autoantibodies (ANAs), myositis-specific autoantibodies (MSAs), and myositis-associated autoantibodies (MAAs) in 6 Latin American countries.
Methods: Two hundred ten patients with IIM were included in this cross-sectional study from 2014 to 2017: 112 from Mexico, 46 from Colombia, 20 from Peru, 16 from the Dominican Republic, 10 from Argentina, and 6 from Guatemala.