Publications by authors named "P C Fitzpatrick"

Breast cancer screening programmes can lead to better disease outcomes, but women from deprived backgrounds are less likely to participate and more likely to present with late-stage cancer. This study aimed to explore associations between deprivation and breast cancer screening outcomes in Ireland during 2009-2018. Data on all female breast cancer cases diagnosed in Ireland during 2009-2018 were extracted from the National Cancer Registry Ireland.

View Article and Find Full Text PDF
Article Synopsis
  • The presentation aims to clarify how flavoproteins perform amine oxidation and explore if monoamine oxidase can cause carbon-carbon bond oxidation.
  • The focus will be on the protonation state of the amine substrate, highlighting that flavoproteins prefer the uncharged form of nitrogen during the oxidation process.
  • The discussion includes insights on L-6-hydroxynicotine oxidase, showing it actually catalyzes carbon-nitrogen bond oxidation rather than carbon-carbon, with key residue analysis aiding in understanding substrate binding.
View Article and Find Full Text PDF

Objective: To investigate a dose-response relationship between the magnitude of decrease in pediatric respiratory tract infections (RTI) during the 2020 implementation of non-pharmaceutical interventions (NPI) and the rise thereafter during NPI lifting.

Study Design: We conducted an interrupted, time-series analysis, based on a multinational surveillance system. All patients <16 years of age coming to medical attention with various symptoms and signs of RTI at 25 pediatric emergency departments from 13 European countries between January 2018 and June 2022 were included.

View Article and Find Full Text PDF

Background: The 'High-Risk Prevention Programme' (HRPP) involved a six-week health behaviour change programme based in general practices and aimed to address cardiovascular disease (CVD) risk in disadvantaged Irish communities.

Objectives: This pilot study aimed to establish the HRPP's likely effectiveness and acceptability to inform the development of a future definitive trial.

Methods: The HRPP was conducted at six general practices in disadvantaged areas in the Ireland East region.

View Article and Find Full Text PDF