Publications by authors named "P C Echeverria"
Article Synopsis
- * It compared 40 PWH divided into two age groups (40-45 and ≥60 years) with 30 HIV-negative controls matched by sex and age.
- * Results indicate that older PWH had more health issues and higher CD8 T cell counts, while younger PWH showed signs of accelerated immune aging and higher inflammatory markers, suggesting a need for early medical interventions.
Introduction: People with the human immunodeficiency virus (PWH) who were diagnosed long ago are more prone to age-related conditions and comorbidities than the general population. We hypothesized that older PWH have endocrine abnormalities that may influence the patient's health status.
Methods: Mean hormonal values across the thyrotropic, somatotropic, corticotropic, and gonadal axis, and percentage of subjects with abnormal values, were compared between PWH aged ≥50 years (n=30) and people without HIV (n=30) (Over50 cohort).
Asymmetric transfer hydrogenation (ATH) is arguably one of the most powerful tools for the synthesis of chiral compounds. Despite tremendous advances in this field, the reduction of α-ketophosphonates remains largely unexplored. Herein, we report an efficient Ru-catalyzed ATH on a broad range of α-ketophosphonates.
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- The study assessed the safety and effectiveness of a two-pill HIV treatment regimen (BIC/FTC/TAF plus darunavir/cobicistat) for individuals with a history of treatment difficulties.
- The trial had 63 participants, mainly men, who were stable on a more complex regimen and showed high rates of maintaining low viral loads after 48 weeks.
- Results indicated the new regimen is well-tolerated, potentially enhancing adherence and long-term success in managing HIV for heavily treatment-experienced individuals.
Emphysematous Kidney Related to the Use of Empagliflozin in a Diabetic Woman.
AACE Clin Case Rep
June 2023
Background/objective: Sodium-glucose cotransporter-2 (SGLT2) inhibitors are part of the treatment for hyperglycemia in patients with diabetes. These drugs have shown important benefits including cardiovascular and renal protection among people with diabetes.
Case Report: We report a case of a 60-year-old woman with diabetes who presented to the emergency department complaining of left flank pain radiating to the groin.