Mortality and Pulmonary Complications of Post-stroke Dysphagia: A Casuistic Review of an Acute Stroke Unit.

Introduction: Dysphagia is a common post-stroke neurological disorder. Early screening for dysphagia can identify patients at risk of aspiration, thereby reducing the occurrence of pulmonary complications, morbidity, and mortality in this population.

Objectives: This study aims to evaluate the impact of an intervention in a stroke unit, following a retrospective study carried out in the same unit in 2020, which investigated the association between dysphagia and acute cerebrovascular disease and analyzed the prevalence of readmissions due to respiratory tract infections (RTI) and mortality.

Implementation of an Oncogeriatric Unit for Frail Older Patients with Breast Cancer: Preliminary Results.

(1) Background: Breast cancer (BC) has a high incidence in Europe, particularly in older adults. Traditionally under-represented in clinical trials, this age group is often undertreated due to ageism. This study aims to characterize frail older adults (≥70 years) with BC based on a comprehensive geriatric assessment, to guide individualized treatment decision-making.

Widening the infantile hypotonia with psychomotor retardation and characteristic Facies-1 Syndrome's clinical and molecular spectrum through NALCN structural analysis.

Introduction: Infantile hypotonia with psychomotor retardation and characteristic facies-1 (IHPRF1, MIM#615419) is a rare, birth onset, autosomal recessive disorder caused by homozygous or compound heterozygous truncating variants in gene (MIM#611549) resulting in a loss-of-function effect.

Methods: We enrolled a new IHPRF1 patients' cohort in the framework of an international multicentric collaboration study. Using specialized pathogenicity predictors and structural analyses, we assessed the mechanistic consequences of the deleterious variants retrieved on NALCN structure and function.

Factors associated with excess weight, hypertension and gestational diabetes in northern Brazil in 2021.

Objective: To estimate the prevalence and factors associated with excess weight, hypertension and diabetes among pregnant women in the northern region of Brazil.

Method: This is a cross-sectional, retrospective study with secondary data conducted with pregnant women living in the northern region of Brazil who took part in the Telephone Survey for Surveillance of Risk and Protective Factors for Chronic Diseases. The chi-square and Kruskal-Wallis tests were used for analysis, as well as the Binomial Logistic Regression model.