Publications by authors named "P Bunn"

Article Synopsis
  • This study investigates the effects of continuing osimertinib alongside platinum-pemetrexed chemotherapy for patients with EGFR mutant non-small cell lung cancer (NSCLC) who have had disease progression on osimertinib.
  • It analyzed data from 159 eligible patients out of 421 identified, comparing outcomes between two groups: one continuing osimertinib with chemotherapy and the other receiving chemotherapy alone.
  • Results showed that the group continuing osimertinib experienced a significant improvement in progression-free survival (9.0 months vs. 4.5 months), indicating a potential clinical benefit in this treatment strategy.
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Introduction: Military personnel confront heightened risks of musculoskeletal injuries (MSIs) because of the demanding nature of their duties, contributing to restricted active duty and financial burdens. Although preventable factors like training and physical fitness influence some injuries, understanding the enduring effects of previous MSIs on physical fitness in military personnel remains a critical gap. This study aimed to systematically review and meta-analyze this impact.

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Article Synopsis
  • Lung cancer is a significant public health challenge with ongoing difficulties in prevention, diagnosis, and treatment, prompting a review of current research and management strategies.
  • Experts from various fields collaborated to discuss ways to enhance lung cancer care, emphasizing the importance of tobacco cessation, early detection, and addressing treatment side effects.
  • Effective lung cancer management requires global cooperation, better education, improved access to care and trials, and a focus on personalized treatment through innovative research.
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Article Synopsis
  • SARS-CoV-2 can spread from asymptomatic individuals, posing a greater risk to cancer patients who frequently visit healthcare facilities and are more vulnerable to severe COVID-19 outcomes.* -
  • A study of lung cancer patients revealed that over half of those with evidence of SARS-CoV-2 infection were asymptomatic at diagnosis, and a significant number were never clinically diagnosed.* -
  • The findings indicate that older patients and those with early-stage lung cancer are more likely to have asymptomatic infections, highlighting the need for continued preventive measures in high-risk populations.*
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