Publications by authors named "P Buehler"

Background: The handover and associated shift start checks by nurses of critical care patients are complex and prone to errors. However, which aspects lead to errors remains unknown. Fewer errors might occur in a structured approach.

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Background: Prehospital point-of-care ultrasound allows an unstable patient to be rapidly and accurately assessed. However, we are concerned that an excessive focus on the ultrasound device, in an already demanding emergency medical service environment, may distract from patient care, potentially leading to reduced situational awareness and the neglect of other crucial instruments, such as the patient monitor. Thus, in this study, we examined the influence of prehospital ultrasound on situational awareness, by studying the degree to which physicians were distracted from the patient monitor.

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Article Synopsis
  • - Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting 500 million people, impairs red blood cell antioxidant functions, raising the risk of hemolysis during oxidative stress, particularly during exercise.
  • - A study using mice with a specific G6PD variant showed that, despite lower enzyme activity, these mice had better exercise performance and improved heart function post-exercise compared to normal mice.
  • - Analysis revealed enhanced mitochondrial function and changes in energy metabolism and protein turnover, indicating that G6PD-deficient individuals might have a metabolic advantage during exercise, challenging existing beliefs about hemolytic risks.
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Article Synopsis
  • Ethical decision-making is crucial in intensive care and emergency medicine, where clinicians often make quick, high-stakes choices under pressure and with limited information.
  • Key principles like patient autonomy, beneficence, non-maleficence, and justice guide these decisions, alongside tools like advanced directives and quality of life assessments.
  • A holistic, multidisciplinary approach is needed, especially for older patients and those with complex health issues, while remaining adaptable in the face of resource limitations and integrating human judgment with technological advancements.
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Sickle cell disease (SCD) is characterized by central (cardiac) and peripheral vascular dysfunctions, significantly diminishing exercise capacity and quality of life. Although central cardiopulmonary abnormalities in SCD are known to reduce exercise capacity and quality of life; the impact of hemolysis and subsequent cell-free hemoglobin (Hb)-mediated peripheral vascular abnormalities on those outcomes are not fully understood. Despite the recognized benefits of exercise training for cardiovascular health and clinical management in chronic diseases like heart failure, there remains substantial debate on the advisability of regular physical activity for patients with SCD.

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