Publications by authors named "P Budhathoki"
Introduction: With advances in therapeutics and longer survival across different cancer spectrums, the incidence of therapy-related acute myeloid leukemia (tAML) has continued to rise. This study aims to evaluate the trend of survival outcomes and their association with sociodemographic factors in tAML over the last 20 years.
Methods: We identified tAML patients between 2000 and 2020 from the Surveillance, Epidemiology, and End Results database.
Background: Cancer screening utilization can aid in the early diagnosis and treatment of cancer. However, the current scenario of the knowledge and practice regarding cancer screening remains unclear as the authors do not have sufficient studies. Hence, the authors conducted this systematic review and meta-analysis to assess the situation of cancer screening utilization and knowledge.
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- - Metabolomics and molecular networking are rapidly growing fields that involve identifying and analyzing bioactive compounds in natural products using advanced mass spectrometry techniques.
- - This study focused on four medicinal plants with unclear biochemical profiles, investigating their ability to inhibit α-amylase and α-glucosidase, important enzymes in carbohydrate digestion.
- - The findings revealed significant inhibition of these enzymes by specific plant extracts, with metabolic profiling identifying 32 secondary metabolites, and the use of GNPS showed extensive data on individual compounds, including many that remain unidentified.
Background: Therapy-related acute myeloid leukemia (tAML) is a serious complication in patients with Non-Hodgkin lymphoma (NHL) exposed to chemotherapy or radiation. This extensive database study aims to quantify the risk of tAML in NHL and determine the impact of tAML on the overall survival (OS) of patients with NHL.
Materials And Methods: Patients diagnosed with NHL and de novo AML from 2009 to 2018 were identified from the Surveillance, Epidemiology, and End Results database.
Purpose: Triple-negative invasive lobular carcinoma (TN-ILC) of breast cancer is a rare disease and the clinical outcomes and prognostic factors are not well-defined.
Methods: Women with stage I-III TN-ILC or triple-negative invasive ductal carcinoma (TN-IDC) of the breast undergoing mastectomy or breast-conserving surgery between 2010 and 2018 in the National Cancer Database were included. Kaplan-Meier curves and multivariate Cox proportional hazard regression were used to compare overall survival (OS) and evaluate prognostic factors.