Publications by authors named "P Brychta"

are bacteria that cause rare infections, typically associated with the infestation of an open wound with fly larvae. Here, we present a unique case report of the first isolation from a burn wound with accidental myiasis in a 63-year-old homeless man and a literature review focused on human infections caused by these bacteria. So far, 23 cases of infection with have been reported; in 52% of these, larvae were found in the wound area.

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Toxic epidermal necrolysis (TEN) is a rare disease, which predominantly manifests as damage to the skin and mucosa. Antibiotics count among the most common triggers of this hypersensitive reaction. Patients with TEN are highly susceptible to infectious complications due to the loss of protective barriers and immunosuppressant therapy.

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Unlabelled: The aim of the study was to identify the most important systemic and local risk factors for the development of infectious complications in patients with toxic epidermal necrolysis (TEN).

Material And Methodology: This is a multicentric study that included all patients with TEN who were hospitalized between 2000-2015 in specialized centres in the Czech Republic and Slovakia. The total catchment area included a population of over 12.

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Introduction: Toxic epidermal necrolysis (TEN) is a rare, life-threatening autoimmune disease predominantly manifested in the skin and mucous membranes. Today, infectious complications have the dominant share in mortality of TEN patients. Due to the nature of the therapy and administration of immunosuppressive medications, a wide range of potentially pathogenic microorganisms, which cause infectious complications in different compartments in these patients, is not surprising.

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Article Synopsis
  • Oleogel-S10, a birch bark extract ointment, was tested in a clinical trial to assess its impact on wound healing in donor sites, focusing on healing time and scar quality over 3 and 12 months.
  • The study reported that patients using Oleogel-S10 experienced faster wound closure (median 7 days) compared to the control group (8 days) and exhibited better scar quality measurements throughout the follow-up period.
  • Additionally, Oleogel-S10 improved scar perfusion and viscoelastic properties, indicating its significant effectiveness in promoting healing at donor sites.
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