Publications by authors named "P Brunori"
Article Synopsis
- A systematic review was conducted to estimate the global prevalence, incidence, and mortality rates of myasthenia gravis (MG) and related syndromes, due to a gap in recent investigations.
- The review analyzed 94 studies published from 1952 to 2022, finding a mean prevalence of 173.3 cases per million, a mean incidence of 15.7 cases per million person-years, and a mean mortality rate of 1.4 cases per million person-years, with acetylcholine receptor (AChR)-MG being the most common subtype.
- The review highlighted that the significant increase in reported MG cases may stem from enhanced research methods and diagnostic tools, though variations in MG frequencies exist due to
Objectives: to estimate Amyotrophic Lateral Sclerosis (ALS) incidence and prevalence in three Italian Regions (Lazio, Tuscany, and Umbria), using health administrative databases.
Design: retrospective population-based study.
Setting And Participants: ALS patients residing in Lazio, Umbria, and Tuscany were identified through an algorithm based on three different administrative databases: hospital discharge records, exemptions from health care co-payment, and emergency departments (study period 2014-2019).
: In the context of a comparative study of efficacy and safety of drugs used in rare neuromuscular and neurodegenerative diseases (CAESAR-call AIFA_FV_2012-13-14), we assessed the use patterns of drugs indicated for myasthenia gravis (MG). : A retrospective cohort study was conducted based on administrative healthcare data. For a cohort of MG patients, prevalent and incident use of pyridostigmine (Py) and other indicated drugs in the first year after case identification was evaluated.
View Article and Find Full Text PDFIntroduction: To evaluate the use of pyridostigmine in presence of contraindications, and the use of concomitant potentially contraindicated drugs in a cohort of patients affected by Myasthenia Gravis (MG) in the Italian Regions of Lazio, Tuscany, and Umbria.
Methods: This is a retrospective cohort study. A multivariate logistic regression model was used to evaluate the determinants of pyridostigmine and of potentially contraindicated drugs use in MG patients.