Publications by authors named "P Brestovansky"

Purpose: The echocardiography parameters may predict the maintenance of sinus rhythm after cardioversion of a supraventricular arrhythmia (SVA).

Materials And Methods: Patients in septic shock with onset of an SVA, normal to moderately reduced LV systolic function (EF_LV˃̳35%) and on a continuous noradrenaline of <1.0 μg/kg.

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Article Synopsis
  • Acute supraventricular arrhythmias can worsen hemodynamic stability in patients with septic shock, and a study compared the effects of intravenous propafenone and amiodarone on arrhythmias in this population.
  • In a trial with 209 patients, those receiving propafenone had a quicker return to sinus rhythm (3.7 hours) compared to those on amiodarone (7.3 hours), although the overall 24-hour sinus rhythm rates were similar.
  • Propafenone led to fewer cases of arrhythmia recurrence than amiodarone, especially in patients without a dilated left atrium, indicating it may be a more effective option for short-term management.
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Purpose: The aim was to verify the impact of obesity on the long-term outcome of patients with severe SARS-CoV-2 ARDS.

Materials And Methods: The retrospective study included patients admitted to the high-volume ECMO centre between March 2020 and March 2022. The impact of body mass index (BMI), co-morbidities and therapeutic measures on the short and 90-day outcomes was analysed.

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Objectives: The aim of the study was to obtain data on demands on the intensive care capacities to treat COVID-19 patients, and to identify predictors for in-hospital mortality.

Methods: The prospective observational multicentre study carried out from 1 March till 30 June 2020 included adult patients with confirmed SARS-CoV-2 infection with respiratory failure requiring ventilatory support or high-flow nasal oxygen therapy (HFNO).

Results: Seventy-four patients, 46 males and 28 females, median age 67.

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Article Synopsis
  • Supraventricular arrhythmias can worsen blood flow issues in patients with septic shock, leading researchers to hypothesize that propafenone might be more effective than amiodarone for restoring normal heart rhythm.
  • The study will involve septic shock patients experiencing new arrhythmias but with stable left ventricular function, randomly assigning them to receive either drug and measuring their rhythm control after 24 hours.
  • Results will also analyze the need for rescue treatments, mortality rates, and factors predicting successful rhythm control and recurrent arrhythmias, with a target enrollment of 200 patients to validate the findings.
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