[Sertraline-induced chronic eosinophilic pneumonia].

Introduction: Sertraline is a selective serotonin reuptake inhibitor which is often used as first-line treatment for depression. Several patterns of interstitial lung disease attributable to sertraline have been reported in the literature.

Case Report: A 69-year-old patient, who had been taking sertraline to treat severe depression for 10 months, presented with a deterioration in his general condition and respiratory symptoms found to be associated with bilateral pneumonitis.

Clinical impact of inspiratory muscle impairment in sarcoidosis.

Background And Aim Of The Work: We evaluated the clinical consequences of inspiratory muscle impairment on exercise tolerance and quality of life in 34 sarcoid patients compared with 19 controls.

Methods: We measured pulmonary function tests, inspiratory muscle strength by maximal inspiratory pressure (PImax) and inspiratory muscle endurance (IME) by an incremental threshold loading test. IME was defined by the maximal sustainable pressure for 2 minutes (Plim2) and Plim2/PImax.

Frequency of cystic fibrosis transmembrane conductance regulator gene mutations and 5T allele in patients with allergic bronchopulmonary aspergillosis.

Study Objective: To assess the frequency of cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in patients with allergic bronchopulmonary aspergillosis (ABPA).

Design: Case-control study. All subjects in the study were screened for the presence of 13 mutations in the CFTR gene (R117H, 621 + 1G(-)>T, R334 W, Delta F508, Delta I507, 1717-1G(-)>A, G542X, R553X, G551D, R1162X, 3849 + 10kbC(-)>T, W1282X, and N1303K).

Lung granulomatosis in a dental technician.

Background: Dental technicians are potentially exposed to various occupational dusts and chemicals. Not surprisingly, occupational related lung diseases have been documented in this population.

Methods: We describe the case of a dental laboratory technician presenting progressive exertional dyspnea and cough.