Risk of bias and problematic trials: characterising the research integrity of trials submitted to Anaesthesia.

Background: There is some evidence for systematic biases and failures of research integrity in the anaesthesia literature. However, the features of problematic trials and effect of editorial selection on these issues have not been well quantified.

Methods: We analysed 209 randomised controlled trials submitted to Anaesthesia between 8 March 2019 and 31 March 2020.

Care of the older trauma patient following low-energy transfer trauma-highlighting a research void.

Background: in high-income countries trauma patients are becoming older, more likely to have comorbidities, and are being injured by low-energy mechanisms. This systematic review investigates the association between higher-level trauma centre care and outcomes of adult patients who were admitted to hospital due to injuries sustained following low-energy trauma.

Methods: a systematic review was conducted in January 2021.