Publications by authors named "P Boudkova"
Article Synopsis
- The study aimed to analyze the sensitization to latex and food allergens in atopic dermatitis patients using the ALEX2 Allergy Xplorer test, comparing the results with personal histories of allergies.
- The study included 100 patients, examining specific IgE responses to latex and collecting detailed allergy histories.
- The findings revealed 17% sensitization to latex, primarily linked to specific protein components, with some patients showing allergic reactions to latex or related fruit syndromes, underscoring the connections between molecular components and clinical reactions.
Our aim is to determine the number of leukocytes, T lymphocytes and B lymphocytes and the expression of activation markers CD200 and CD23 on B lymphocytes in atopic dermatitis (AD) patients (treated and not treated with dupilumab) during the pollen season. We examined 29 patients not treated with dupilumab, 24 patients treated with dupilumab and 40 healthy subjects as a control group. The count of T and B lymphocytes and their subsets were assessed by flow cytometry.
View Article and Find Full Text PDFBackground: Natural killer cells (NK) and innate lymphoid cells with their subsets (ILC) are part of the innate immune system.
Objective: The aim is to evaluate how NK cells and ILC cells interact in atopic dermatitis (AD) patients (with and without dupilumab therapy) compared to control group.
Materials And Methods: Complete dermatological examination was performed in all patients included in the study (19 AD patients with dupilumab, 17 AD patients without dupilumab).
Article Synopsis
- - Ramsay-Hunt syndrome occurs when the varicella-zoster virus reactivates, leading to facial paralysis, ear pain, and blisters around the ear.
- - Treatment usually includes antiviral drugs, corticosteroids, and pain relief.
- - A 45-year-old patient with severe atopic dermatitis developed Ramsay-Hunt syndrome while on dupilumab; continuing dupilumab with low-dose acyclovir was deemed necessary due to worsening of asthma and dermatitis upon stopping the treatment.
Background: Eosinophils and basophils are implicated in allergic reactions, and the molecule CD200 on B cells may have regulatory functions. Assessing the associations between the expression of CD200 on B lymphocytes and eosinophils and basophils helps unravel the complex immune interactions in atopic dermatitis, aiding in targeted therapeutic approaches.
Objective: The aim of our study is to evaluate the association between the count of eosinophils, basophils, CD16 eosinophils, CD203 basophils, the expression of activation marker CD200 on B cells and on their subsets in patients suffering from atopic dermatitis with and without dupilumab and in control group.