Publications by authors named "P Bottin"
Purpose: Only a few case reports have described heterotopic ovarian tissue transplantation (OTT) with the only objective of restoring ovarian function.
Methods: Case report and review of the literature for reporting cases of heterotopic OTT with the only aim of restoring ovarian endocrine function. In a cancer survivor woman with a history of hysterectomy and bilateral oophorectomy for cervical cancer and because she poorly tolerated hormone replacement therapy (HRT), we performed a heterotopic OTT in a pelvic subcutaneous "pocket" after an OT cryostorage of 17 years.
The aim of our study was to evaluate the feasibility and efficiency of delayed ovarian stimulation and metaphase II oocyte banking for fertility preservation after fertility-impairing treatment regardless of the initial disease. We conducted a cohort study based on population of women < 40 years of age with diminished ovarian reserve caused by fertility-impairing treatment (n = 129). Three groups of women were compared according to the type of initial disease: hematological malignancies, solid tumors, and benign diseases.
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- The study investigates the effectiveness of a specialized E-Meeting for fertility preservation specialists to discuss complex oncofertility cases over a three-year period.
- Since its launch in September 2016, 104 experts have participated, with 109 challenging cases submitted, primarily involving young female patients with an average age of 22.4 years.
- The platform facilitated diverse expert strategies for patient care, improved practitioners' confidence in their plans, and highlighted the importance of collaborative communication among specialists to enhance patient management.
Fertility preservation after fertility-sparing surgery in women with borderline ovarian tumours.
Eur J Obstet Gynecol Reprod Biol
October 2020
Objective: To present a case series of women with borderline ovarian tumours (BOTs) who underwent oocyte vitrification in addition to fertility-sparing surgery.
Study Design: Observational study of all women referred to a French fertility preservation unit between 2015 and 2019 for counselling regarding a fertility preservation (FP) strategy after BOT fertility-sparing surgery. All eligible women underwent one or more cycles of controlled ovarian stimulation (COS) using an antagonist protocol, followed by oocyte retrieval.