Publications by authors named "P Boscolo"
Therapeutic innovation is expected to change if not disrupt present care models for several chronic diseases in the coming years, as suggested by recent clinical trials. New drugs that anticipate and possibly delay the full expression of a disease will likely face some common challenges, such as the need of designing and implementing large scale interventions; the necessary engagement of multiple specialties for both diagnosis and treatment; the shift from specialist to non-specialist interventions and secondary prevention. Building on the case of HCV and other innovation in hepatology, we discuss common challenges caused by disruptive change that other chronic conditions faced in the past.
View Article and Find Full Text PDFBackground: Writing is a particularly demanding activity, which poses unique motivational challenges for students. Despite the wealth of research on the relation between writing motivation and writing performance, little is known about the role of students' writing frequency in writing motivation and writing performance.
Aims: We aimed to: (1) examine structural relations among two motivational variables (i.
Purpose: This paper presents a comparative analysis of value-based frameworks (VBFs) developed in the United States and Europe for both drugs and medical devices.
Methods: The authors relied on a comprehensive literature review to identify relevant dimensions of analysis and available VBFs. Compared to previous studies on this topic, this study focused on the roles and strategic objectives of different institutions and organizations currently orchestrating the debate and development of VBFs and value-based initiatives.
The objective of this mini-review is to discuss the role of real-world studies as a source of clinical evidence when experimental studies, such as randomised controlled trials (RCTs), are not available. Waiting for RCT evidence when the technology is diffusing could be anti-economical, inefficient from the policy perspective and methodologically questionable.We explain how real-world studies could provide relevant evidence to decision makers.
View Article and Find Full Text PDFArticle Synopsis
- Manual activities in construction, specifically for painters, can lead to musculoskeletal disorders, prompting a study to assess spinal movements and upper limb risks using tools like lumbar motion monitors and cameras.
- The study found that using a roller is generally safer for the upper limbs compared to a brush, but using a roller-stick of incorrect length can strain the back.
- To minimize risk according to the OCRA Index, painters should limit vertical wall painting to 3 hours with a roller and 2.5 hours with a brush; on average, a painter lifts a bucket about 120,140 times during a 5-hour workday.