Six-year prospective multicenter randomized comparison of autologous saphenous vein and expanded polytetrafluoroethylene grafts in infrainguinal arterial reconstructions.

Autologous saphenous vein (ASV) and polytetrafluoroethylene (PTFE) grafts were compared in 845 infrainguinal bypass operations, 485 to the popliteal artery and 360 to infrapopliteal arteries. Life-table primary patency rates for randomized PTFE grafts to the popliteal artery paralleled those for randomized ASV grafts to the same level for 2 years and then became significantly different (4-year patency rate of 68% +/- 8% [SE] for ASV vs. 47% +/- 9% for PTFE, p less than 0.

Lessons learned in adopting the in situ saphenous vein bypass.

A 3-year experience with in situ saphenous vein bypasses was analyzed to evaluate the suitability of the conduit, the effect on vein utilization rate, the ease of valve ablation, the incidence of persistent arteriovenous (AV) fistula, the duration of the operation, and the nature of the learning curve to become adept at this technique. From 1981 through 1983, 74 patients underwent 55 femoral-tibial and 23 femoral-popliteal in situ saphenous vein bypasses. The operative indications were threatened limb loss in 76 (97%) and disabling claudication in 2 (3%); 35 of 74 patients (48%) were diabetic.