Publications by authors named "P Bonelli"

Cystic and alveolar echinococcosis are severe zoonotic diseases characterized by long asymptomatic periods lasting months or years. Viable Echinococcus spp. eggs released into the environment through the feces of canids can infect humans through accidental ingestion via hand-to-mouth contact or consumption of contaminated food or water.

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  • * These micropeptides can either suppress or promote tumors, making them potential biomarkers for early cancer diagnosis and targets for therapy.
  • * The review explores the roles of micropeptides from long non-coding RNAs, microRNAs, and circular RNAs in various cancers, while also addressing current challenges and future research directions in this area of cancer biology.
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  • Porcine parvoviruses (PPVs) are major contributors to reproductive issues in pigs globally, with eight genetic variants identified across four genera.
  • PPV7, first found in the USA in 2016, has spread to Europe, Asia, and South America, and was detected in pig farms in Italy facing reproductive challenges.
  • In a study conducted in Sardinia, PPV7 was found in 20.59% of domestic and wild pig samples, with higher co-infection rates of Porcine Circovirus 2 and 3 in PPV7-positive pigs, and molecular analysis revealed a high frequency of viral recombination.
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: Dapagliflozin has shown efficacy in clinical trials in patients with heart failure and reduced ejection fraction (HFrEF). However, real-world data on its use and outcomes in routine clinical practice are limited. We aimed to evaluate the utilisation and safety profile of dapagliflozin in a real-world population of HFrEF patients within the Marche region.

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  • This study introduces a method for effectively removing template molecules from molecularly imprinted polymers using heat-activated persulfate, addressing issues with incomplete template removal seen in current techniques.
  • The research utilized a polymer designed for Coenzyme Q extraction to test this new approach, ensuring that the heat treatment accurately eliminated the template without compromising the polymer's performance.
  • Results showed that this method is efficient and eco-friendly, providing comparable selectivity for target analytes to traditional methods, marking a significant improvement in trace analysis applications.
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