Publications by authors named "P Blin"
Non-steroidal anti-inflammatory drugs (NSAIDs) are the second most widely used class of analgesics in France, after paracetamol. Some NSAIDs are available over the counter (OTC), without a prescription, on the advice of a pharmacist. NSAIDs have recently been the subject of safety alerts from France's Agence nationale de sécurité du médicament et des produits de santé (ANSM), highlighting a risk of worsening certain bacterial infections.
View Article and Find Full Text PDFPurpose: This paper aims to introduce an algorithm designed to identify Venous Thromboembolism (VTE) in the French National Healthcare Database (SNDS) and to estimate its positive predictive value.
Methods: A case-identifying algorithm was designed using SNDS inpatient and outpatient encounters, including hospital stays with discharge diagnoses, imaging procedures and drugs dispensed, of French patients aged at least 18 years old to whom baricitinib or Tumor Necrosis Factor Inhibitors (TNFi) were dispensed between September 1, 2017, and December 31, 2018. An intra-database validation study was then conducted, drawing 150 cases identified as VTE by the algorithm and requesting four vascular specialists to assess them.
Article Synopsis
- The study investigated the incidence and costs associated with cardiovascular renal diseases (CVRD) among people with type 2 diabetes who did not have a history of CVRD, using a cohort of over 2 million individuals in France for 5 years.
- Results showed that 15.3% of participants developed a CVRD manifestation within 5 years, with chronic kidney disease (CKD) being the most common (40.6%), followed by heart failure (HF) and peripheral arterial disease (PAD).
- The total hospitalization costs for CVRD over the 5 years were estimated at 3.9 billion euros, with CKD accounting for the largest share of the costs (2 billion euros), indicating a significant economic burden in
Background: Healthcare pathways of patients with prostate cancer are heterogeneous and complex to apprehend using traditional descriptive statistics. Clustering and visualization methods can enhance their characterization.
Methods: Patients with prostate cancer in 2014 were identified in the French National Healthcare database (-SNDS) and their data were extracted with up to 5 years of history and 4 years of follow-up.
Article Synopsis
- A study utilized data from the French national health insurance database to analyze the effectiveness of various osteoporosis medications (denosumab, zoledronic acid, oral bisphosphonates, raloxifene, and teriparatide) on reducing fracture risk in women over 55 years old.
- It followed five cohorts and compared fracture incidences over two years after starting treatment, highlighting a significant reduction in vertebral fractures for all medications.
- While denosumab showed efficacy in reducing hip fracture risk and nonvertebral fractures, oral bisphosphonates displayed an increased risk for hip fractures, indicating varied effectiveness among the treatments in real-world conditions.