Publications by authors named "P Binitha Manikoth"

Background: Therapeutic hypothermia (TH) is the standard treatment for moderate to severe hypoxic-ischemic encephalopathy (HIE) in developed countries, but data on its safety and efficacy in low-middle-income countries are limited and often conflicting. The impact of enteral feeding during TH remains inadequately explored. We aimed to examine TH's effects on mortality and brain injury and evaluate the safety and effectiveness of minimal enteral feeding during TH.

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Background: The Global Dementia Observatory (GDO) is a monitoring and accountability tool for the Global Action Plan on Public Response to Dementia 2017-25. Evidence from dementia registries may be utilized to better address WHO efforts in member countries, as well as to improve clinical practice and public health policy. The goal of this study was to analyze one-year data from a prospective memory clinic registry.

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Article Synopsis
  • The study aimed to implement the Age-Friendly Health Systems (AFHS) 4Ms framework, particularly focusing on how medication affects Mobility, Mentation, and What Matters for older adults at Hamad Medical Corporation in Qatar.
  • A quality improvement approach was utilized, highlighting the relationship between high-risk medications and their impacts, while developing tools and templates for better medication management through interdisciplinary collaboration.
  • The successful implementation of the framework improved patient-centered care and caregiver engagement, emphasizing the importance of teamwork in medication management for better health outcomes in older adults.
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Objectives: This study compared the utility of corneal nerve measures with brain volumetry for predicting progression to dementia in individuals with mild cognitive impairment (MCI).

Methods: Participants with no cognitive impairment (NCI) and MCI underwent assessment of cognitive function, brain volumetry of thirteen brain structures, including the hippocampus and corneal confocal microscopy (CCM). Participants with MCI were followed up in the clinic to identify progression to dementia.

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