Publications by authors named "P Benedikt"
Article Synopsis
- The study aimed to explore differences in characteristics and 2-year outcomes after surgical aortic valve replacement (SAVR) between males and females, using data from two registries involving 933 patients.
- Females had certain clinical differences such as lower body mass index, higher surgical risk scores, and smaller valves compared to males, but these disparities largely disappeared after adjusting for similar baseline characteristics.
- Ultimately, despite a higher initial surgical risk profile, both sexes had comparable outcomes 2 years post-SAVR, indicating no significant differences in overall results based on sex.
Objectives: Although the Perceval sutureless aortic valve bioprosthesis presents a feasible alternative to conventional aortic valve prostheses, the extent of its applicability with respect to technical considerations for a real-world patient collective is still under debate.
Methods: One hundred patients received the Perceval prosthesis [males: 59; age: 72.5 (7.
Introduction: The frozen elephant trunk technique (FET) has become routine for aortic arch and descending aortic repair. New hybrid prosthesis models are constantly being developed to increase effectiveness and durability of aortic repair. Recently, concerns were raised regarding increased post-operative bleeding using a new-generation hybrid prosthesis (E-vita OPEN NEO, CryoLife Inc.
View Article and Find Full Text PDFBackground: Degenerative aortic valve disease accounts for 10-20% of all cardiac surgical procedures. The impact of pre-existing comorbidities on the outcome of patients undergoing surgical aortic valve replacement (SAVR) needs further research.
Methods: The IMPACT registry is a non-interventional, prospective, open-label, multicenter, international registry with a follow-up of 5 years to assess the impact of pre-existing comorbidities of patients undergoing SAVR with the INSPIRIS RESILIA aortic valve on outcomes.
Murine hepatic carboxylesterase 2c () and the presumed human ortholog carboxylesterase 2 () have been implicated in the development of nonalcoholic fatty liver disease (NAFLD) in mice and obese humans. These studies demonstrated that hydrolyzes triglycerides (TGs) in hepatocytes. Interestingly, / is most abundantly expressed in the intestine, indicating a role of / in intestinal TG metabolism.
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