Publications by authors named "P Bassett"

Aim: Pilonidal disease is a benign condition mainly affecting the young population. In recent literature, the depth of the natal cleft is thought to impact postoperative outcomes including wound complications and rate of recurrence. Currently there is no agreed method for measuring the depth of the natal cleft; this study proposes a novel and instrument-free technique that can be used as a research tool to measure the depth.

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Background: Prostate specific antigen density (PSAd) is one of the strongest predictors of clinically-significant prostate cancer (csPCa) in risk calculators. There is little evidence on the effect of prostate volume on the diagnostic performance of PSAd. Our aim was to define the diagnostic accuracy of PSAd for predicting csPCa across prostate volumes.

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Background: There has been significant reduction in inpatient beds for people with intellectual disability and/or autism (PwID/A) in the UK in the last decade following high profile national scandals in specialist psychiatric hospitals. To reduce inappropriate admissions a new strategy (Blue-Light, an emergency multi-disciplinary meeting to prevent admission to hospital) was introduced. However, there is no research on the influence of Blue-Light on crisis management for PwID/A.

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Article Synopsis
  • Patients with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) have a significant risk of developing colorectal cancer, and there's no consensus on the best surveillance methods.
  • A study analyzed 91 patients with PSC and IBD over ten years to evaluate how effective chromoendoscopy and high-definition endoscopy were in detecting neoplastic lesions during regular check-ups.
  • Results showed that chromoendoscopy greatly increased the detection rate of neoplasia (by 5.58 times), while high-definition endoscopy also improved detection, but its significance diminished when factoring in chromoendoscopy.
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Amyloidogenic transthyretin (ATTR) amyloidosis is a systemic disease characterized by the deposition of amyloid fibrils made of transthyretin. Transthyretin is primarily produced in tetrameric form by the liver, but also by retinal epithelium and choroid plexus. The deposition of these fibrils in the myocardium and peripheral nerves causes cardiomyopathies and neuropathies, respectively.

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