Publications by authors named "P Barthet"
Article Synopsis
- Periodontitis poses significant health risks, including tooth loss and aggravated chronic diseases, impacting overall health and quality of life.
- Effective periodontal treatment starts with etiological therapy, focusing on oral hygiene and managing risk factors to reduce bacterial load and inflammation.
- While non-surgical debridement is crucial for treatment, the use of adjunctive therapies is limited by a lack of clear clinical guidelines, highlighting the need for standardized research and ongoing patient monitoring.
The aim of this study was to analyze the link between oral microbiota and obesity in humans. We conducted a pilot study including 19 subjects with periodontitis divided into two groups: normo-weighted subjects (NWS) with a body mass index (BMI) between 20 and 25 ( = 9) and obese subjects (OS) with a BMI > 30 ( = 10). Obesity was associated with a poor oral health status characterized by an increased number of missing teeth and a higher score of periodontal-support loss associated with dysbiotic oral microbiota (39.
View Article and Find Full Text PDFObjectives: Previous studies have shown that metronidazole, alone or in combination with spiramycin (250 mg/1 500 000 units, three times/day), is an effective treatment for active periodontitis, although the dose of metronidazole currently used (750 mg/day) could provide concentrations in gingival crevice fluid that are too low for the MICs of the involved pathogens. This study tested the in vivo antibacterial efficacy of the currently used metronidazole dose (as contained in the fixed spiramycin/metronidazole combination) in patients with an active periodontitis, and of a high dose (1500 mg/day) of metronidazole alone.
Methods: We measured the MICs of spiramycin and metronidazole for the recovered pathogens and the gingival crevice fluid antibiotic concentrations of both antibiotics, and attempted to correlate them with bacterial eradication.
A multicenter report on 1,022 consecutively placed ITI implants: a 7-year longitudinal study.
Int J Oral Maxillofac Implants
November 2000
The aim of this multicenter study was to evaluate cumulative success and survival rates of ITI implants after 7 years. A complete medical report was obtained for all 440 patients enrolled in this investigation, which involved 10 different private practices. The 1,022 consecutively placed implants were distributed between completely edentulous, partially edentulous, and single-tooth replacement cases.
View Article and Find Full Text PDFBackground: This investigation was designed to evaluate the involvement of Fusobacterium nucleatum clinical strains in adult periodontitis by subspecies and expression of hemagglutination activity.
Methods: Forty-nine Fusobacterium strains were isolated from 40 sites in 40 subjects presenting with adult periodontitis. F.