Publications by authors named "P Baptiste"
Article Synopsis
- * A study analyzing data from over 570,000 patients in the UK focused on the effectiveness and safety of ARBs compared to ACEis among Black, South Asian, and White populations, revealing similar event rates for cardiovascular issues in both drug groups.
- * The analysis showed no significant differences in treatment outcomes by ethnicity, providing a hazard ratio of 0.96 for major cardiovascular events and suggesting that ARBs and ACEis have comparable effectiveness across
Background: Stroke prevention guidance for patients with atrial fibrillation (AF) uses evidence generated from randomised controlled trials (RCTs). However, applicability to patient groups excluded from trials remains unknown. Real-world patient data provide an opportunity to evaluate outcomes in a trial analogous population of direct oral anticoagulants (DOACs) users and in patients otherwise excluded from RCTs; however, there remains uncertainty on the validity of methods and suitability of the data.
View Article and Find Full Text PDFCardiovascular disease is a leading cause of death globally. Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB), compared in the ONTARGET trial (Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial), each prevent cardiovascular disease. However, trial results may not be generalizable, and their effectiveness in underrepresented groups is unclear.
View Article and Find Full Text PDFAim: This prospective cohort study investigated the association between periodontal diseases (PDs) and all-cause and cause-specific mortality.
Materials And Methods: We utilized adult participants recruited from six National Health and Nutrition Examination Survey cycles (1999-2014) and linked mortality data from the National Death Index up to December 2019. Baseline clinical periodontal examinations were performed by trained and calibrated examiners.