Background: Alterations in skin blood flow is a marker of inadequate tissue perfusion in critically ill patients after initial resuscitation. The effects of red blood cell transfusions (RBCT) on skin perfusion are not described in this setting. We evaluated the effects of red blood cell transfusions on skin tissue perfusion in critically ill patients without acute bleeding after initial resuscitation.
View Article and Find Full Text PDFBackground: Heart rate variability (HRV) may provide an estimation of the autonomous nervous system (ANS) integrity in critically ill patients. Disturbances of cerebral autoregulation (CAR) may share common pathways of ANS dysfunction.
Aim: To explore whether changes in HRV and CAR index correlate in critically ill septic patients.
Background: Continuous veno-venous hemofiltration (CVVH) can be used to reduce fluid overload and tissue edema, but excessive fluid removal may impair tissue perfusion. Skin blood flow (SBF) alters rapidly in shock, so its measurement may be useful to help monitor tissue perfusion.
Methods: In a prospective, observational study in a 35-bed department of intensive care, all patients with shock who required fluid removal with CVVH were considered for inclusion.
Background: Optimal transfusion practice remains a matter of ongoing debate despite several large clinical studies.
Study Design And Methods: Databases from two observational studies-the Anemia and Blood Transfusion in Critically ill patients (ABC) conducted in 1999 and The Intensive Care Over Nations (ICON) audit conducted in 2012-were compared to evaluate changes in transfusion practice and outcomes over a 13-year period.
Results: A total of 3534 patients from the ABC study and 4125 from the ICON study were included in this analysis.