Publications by authors named "P BURTIN"

Background: Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of death by cancer worldwide. Mostly diagnosed with locally advanced or metastatic disease, patients lack treatment options. Gene alterations (GAs) are frequently observed in PDAC, some of which are considered for molecular targeted therapies (MTTs), with potential clinical benefits and improved outcomes.

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Article Synopsis
  • The study examines the impact of surgically addressing non-R0 resections of rectal neuroendocrine tumors (r-NETs) to prevent disease recurrence.
  • It involved a retrospective analysis of 100 patients who underwent endoscopic procedures to remove tumor scars after initial unsuccessful resections.
  • The findings indicate that using advanced endoscopic techniques achieved near 100% complete resection (R0) of scars, revealing that residual r-NET was present in 43% of cases.
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  • The term "juvenile-like (hyperplastic/inflammatory) mucosal polyp" describes rare benign growths in the gastrointestinal tract, primarily linked to type 1 neurofibromatosis (NF1).
  • A novel case was reported involving a 53-year-old woman with a large polyp in the cecum that exhibited characteristics of inflammation and specific cellular composition, resembling juvenile polyps.
  • Whole exome sequencing revealed a pathogenic variant associated with her condition, suggesting that juvenile-like inflammatory polyps can occur independently of NF1 and warrant further examination in complex gastrointestinal tumors.
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Pediatric cardiac anesthesia is a subspecialty of cardiac and pediatric anesthesiology dedicated to the perioperative care of patients with congenital heart disease. Members of the Congenital and Education Subcommittees of the European Association of Cardiothoracic Anaesthesiology and Intensive Care (EACTAIC) agreed on the necessity to develop an EACTAIC pediatric cardiac anesthesia fellowship curriculum. This manuscript represents a consensus on the composition and the design of the EACTAIC Pediatric Cardiac Anesthesia Fellowship program.

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