Publications by authors named "P BOULANGER"
Article Synopsis
- The study aimed to understand how patients with myasthenia gravis (MG) perceive their condition and identify potential improvements in treatment.
- Patients over 12 months with the disease participated in an online survey, resulting in 246 completed responses.
- Key findings highlighted participants' desires for better physical activity, reduced fatigue, and suggested treatment improvements, including fewer side effects and simpler medication regimens.
Improving Cranial Vault Remodeling for Unilateral Coronal Craniosynostosis-Introducing Automated Surgical Planning.
Craniomaxillofac Trauma Reconstr
September 2024
Article Synopsis
- The study introduces automated surgical planning for cranial vault remodeling (CVR) in cases of unicoronal synostosis, specifically focusing on the challenges posed by the asymmetric nature of this deformity.
- Using software like Geomagic Freeform Plus, researchers developed virtual workflows that involved comparing reconstructed skull models to normal skull parameters through various measurements, resulting in different performance ratings.
- The findings showed significant advancements in key skull areas with the highest performing model closely matching a normal skull, marking a groundbreaking approach to improving surgical outcomes in asymmetric craniosynostosis.
Computed tomography perfusion (CTP) is a dynamic 4-dimensional imaging technique (3-dimensional volumes captured over approximately 1 min) in which cerebral blood flow is quantified by tracking the passage of a bolus of intravenous contrast with serial imaging of the brain. To diagnose and assess acute ischemic stroke, the standard method relies on summarizing acquired CTPs over the time axis to create maps that show different hemodynamic parameters, such as the timing of the bolus arrival and passage (Tmax and MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV). However, producing accurate CTP maps requires the selection of an arterial input function (AIF), i.
View Article and Find Full Text PDFThe promises of vaccines based on virus-like particles stimulate demand for universal non-infectious virus-like platforms that can be efficiently grafted with large antigens. Here, we harnessed the modularity and extreme affinity of the decoration protein pb10 for the capsid of bacteriophage T5. SPR experiments demonstrated that pb10 fused to mCherry or to the model antigen ovalbumin (Ova) retained picomolar affinity for DNA-free T5 capsid-like particles (T5-CLPs), while cryo-EM studies attested to the full occupancy of the 120 capsid binding sites.
View Article and Find Full Text PDFPaediatric heart transplant recipients (HTRs) have reduced exercise capacity, physical activity (PA), health-related quality of life (HRQoL), and self-efficacy towards PA. Exercise interventions have demonstrated improvements in exercise capacity and functional status in adult HTRs, with a specific emerging interest in the role of high-intensity interval training (HIIT). Studies of exercise interventions in paediatric HTRs have been limited and nonrandomized to date.
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