Publications by authors named "P B Simpson"

Planning research involving people in prison raises concerns based on past abuses of incarcerated people amongst other factors. Despite the development of guidelines for the ethical conduct of research in prisons, researchers and advocates have questioned whether current approaches aimed at protecting incarcerated persons from unethical research unfairly exclude this group from participating in and benefitting from research. Discussion of these issues comes mostly from expert opinion.

View Article and Find Full Text PDF

Objectives: Cyclic vomiting syndrome (CVS) remains a diagnostic challenge due to its nonspecific presentation despite consensus-based diagnostic criteria. There is a need for improved, evidence-based diagnostic criteria. We hypothesized that symptoms differ quantitatively between children with CVS versus other vomiting conditions and that current diagnostic criteria are not sufficiently sensitive for diagnosing CVS.

View Article and Find Full Text PDF

Background: During the COVID-19 pandemic, outpatient waits for gynaecology appointments increased by 60% in the UK National Health Service (NHS). The aim of this study was to use the electronic Personal Assessment Questionnaire-Menstrual, Pain and Hormonal (ePAQ-MPH) electronic patient reported outcome measure (ePROM) to assess symptoms, impact and potential harm for patients waiting > 60 weeks for general gynaecology appointments at a teaching hospital.

Methods: 1070 patients waiting > 60 weeks for a new appointment (range 60-72 weeks) were invited to complete ePAQ-MPH online to measure gynaecological symptoms and health-related quality-of-life (HRQoL).

View Article and Find Full Text PDF

: variants are the most well-known genetic risk factor (10%) for hypoplastic left heart syndrome (HLHS) and are associated with decreased cardiac transplant-free survival. encodes for α-myosin heavy chain (α-MHC), a contractile protein expressed in the neonatal atria. We therefore assessed atrial function in HLHS patients with variants.

View Article and Find Full Text PDF
Article Synopsis
  • The study explores the emerging field of epidemiological criminology, focusing on the relationship between public health and justice systems, while identifying knowledge gaps in existing research.
  • By analyzing 34,481 PubMed abstracts from 1963 to 2023, the study highlights that nearly half of these abstracts lack population characteristic details, with only a small percentage providing comprehensive demographic information.
  • Findings reveal a significant increase in research on female populations, which now surpasses that on males, raising concerns about the underrepresentation of male prisoners in studies, despite them making up the majority of the incarcerated population.
View Article and Find Full Text PDF