Publications by authors named "P B Hoyer"
Background: There is a lack of information on the current healthcare systems for children with kidney diseases across Europe. The aim of this study was to explore the different national approaches to the organization and delivery of pediatric nephrology services within Europe.
Methods: In 2020, the European society for Paediatric Nephrology (ESPN) conducted a cross-sectional survey to identify the existing pediatric nephrology healthcare systems in 48 European countries covering a population of more than 200 million children.
Objectives: The shape is commonly used to describe the objects. State-of-the-art algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from the growing popularity of ShapeNet (51,300 models) and Princeton ModelNet (127,915 models).
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- Treatment for advanced pediatric rhabdomyosarcoma with peritoneal sarcomatosis involves a combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), but the ideal drug dosages and combinations have not been well-studied.
- An in vivo mouse model was created to test the efficacy of different doses of cisplatin and doxorubicin in HIPEC, finding that certain dosages significantly reduced the extent of tumor spread, indicated by the peritoneal cancer index (PCI).
- Results showed that a combination of lower doses of both drugs had the best effect on reducing tumor spread, suggesting that further research is needed to fully understand the treatment's impact and improve strategies.
Background: Kidney transplantation (KTx) from small donors is associated with inferior graft survival in registry studies, whereas single-center studies show favorable results.
Methods: We compared 175 pediatric KTx from small donors ≤20 kg (SDKTx) with 170 age-matched recipients from adult donors (ADKTx) from 20 centers within the Cooperative European Paediatric Renal Transplant Initiative registry. Graft survival and estimated glomerular filtration rate (eGFR) were analyzed by Cox regression and mixed models.
Background: Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue malignancy, characterized by high clinicalopathological and molecular heterogeneity. Preclinical models are essential for advancing our understanding of RMS oncobiology and developing novel treatment strategies. However, the diversity of scholarly data on preclinical RMS studies may challenge scientists and clinicians.
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