Publications by authors named "P B Cassidy"
Article Synopsis
- There is currently no FDA-approved treatment for pityriasis rubra pilaris (PRP), and many patients do not see improvement with existing systemic therapies, highlighting the potential role of interleukin-23 as a therapeutic target.
- This study aimed to assess the effectiveness of guselkumab, an IL-23p19 inhibitor, in improving PRP symptoms and to explore related gene and protein dysregulation.
- The trial involved 14 adults, with results showing significant improvements in skin severity and quality of life, where 75% of participants experienced meaningful clinical responses by the end of the 24-week treatment period.
Background: We described changes in 2016─2020 carbapenem-resistant Enterobacterales (CRE) incidence rates in 7 US sites that conduct population-based CRE surveillance.
Methods: An incident CRE case was defined as the first isolation of , spp., or spp.
Background: Despite progress, stillbirth rates in many high- and upper-middle income countries remain high, and the majority of these deaths are preventable. We introduce the Ending Preventable Stillbirths (EPS) Scorecard for High- and Upper Middle-Income Countries, a tool to track progress against the Lancet's 2016 EPS Series Call to Action, fostering transparency, consistency and accountability.
Methods: The Scorecard for EPS in High- and Upper-Middle Income Countries was adapted from the Scorecard for EPS in Low-Income Countries, which includes 20 indicators to track progress against the eight Call to Action targets.
Article Synopsis
- Nontuberculous mycobacteria (NTM) infections are challenging to diagnose and treat, affecting both the lungs (PNTM) and other parts of the body (ENTM) in various settings, including healthcare.
- A pilot study by the CDC involved NTM surveillance across four U.S. sites, collecting patient data from October 2019 to March 2020, and found 299 reported cases, with the majority being pulmonary.
- The study's findings highlight the need for active surveillance to better understand NTM prevalence and characteristics of affected populations, which can inform future healthcare interventions.
This article explores the contexts, processes and motivations behind the administration of sedatives (minor tranquilisers) in the time around perinatal loss. Using a mixed methods design, an online survey of 796 women and 13 narrative interviews were conducted. The participants had experienced a stillbirth or termination of pregnancy from 16 weeks or a neonatal death in Spanish hospitals.
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