Publications by authors named "P B Bourgeois"
Article Synopsis
- Immunosuppressive medication dosing after organ transplantation typically relies on therapeutic drug monitoring, but this method may not effectively predict rejection or infections.
- The TTVguideIT trial investigates using Torque Teno Virus (TTV) load measurement via qPCR as a potentially better alternative for dosing tacrolimus.
- Results demonstrated that the TTV R-GENE® assay showed excellent accuracy and consistency across participating labs, allowing for standardized TTV load measurement in clinical trials.
Article Synopsis
- The study evaluated postoperative outcomes in 9 patients with unruptured giant middle cerebral artery (MCA) aneurysms linked to intracranial hypertension and midline brain shift from 2012 to 2022.
- Four patients underwent deep hypothermic circulatory flow reduction while five received cerebral revascularization with aneurysm trapping, with outcomes monitored early and long-term.
- Postoperative complications included diffuse cerebral edema and neurological deterioration, with suggestions for decompressive hemicraniotomy and improved blood flow assessment to enhance recovery.
Introduction: The etiology of brain aneurysms remains poorly understood. Finnish research suggests that oral bacteria might contribute to the development and rupture of brain aneurysms. Previous studies by our team have not confirmed these findings, likely due to methodological differences.
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