Publications by authors named "P B BRADLEY"

This study aimed to benchmark the match demands of specialised positions at the FIFA Women's World Cup Australia and New Zealand 2023. With FIFA's official approval, all sixty-four games at the tournament were analysed using an optical tracking system alongside FIFA's Enhanced Football Intelligence metrics. During a typical match, defensive and central midfielders covered 5-15% more total distance than centre backs, wide defenders and centre forwards (P < 0.

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Background: Humans are primary drivers of environmental-contaminant exposures worldwide, including in drinking-water (DW). In the United States, point-of-use DW (POU-DW) is supplied via private tapwater (TW), public-supply TW, and bottled water (BW). Differences in management, monitoring, and messaging and lack of directly-intercomparable exposure data influence the actual and perceived quality and safety of different DW supplies and directly impact consumer decision-making.

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The capacity for a non-native species to become invasive largely hinges on existing dispersal capacity or adaptation of dispersal in new environments. Here we provide early evidence that invasive Northern Pike (Esox lucius), a Holarctic freshwater top predator, illegally introduced in the late 1950s into Southcentral Alaska, are now dispersing through estuarine corridors. This finding represents the first known documentation of estuary use and dispersal by Northern Pike in North America, exacerbating conservation concerns for already depressed populations of culturally and economically important species such as salmonids.

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Background: Over 200,000 patients are referred onto the suspected head and neck cancer (HNC) pathway annually in the UK, with around 3% receiving a cancer diagnosis. With new HNC advancements in identifying patients at low risk of a cancer diagnosis, one proposal is a speech and language therapy (SLT)-led first point of contact clinic for low-risk patients presenting with voice or swallowing symptoms.

Aims: To explore ear, nose and throat (ENT) surgeons' views regarding this model.

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Article Synopsis
  • Xenobiotics, such as pharmaceutical drugs, can be metabolized by both human hosts and gut microbiota, with some human proteins having microbial counterparts known as homologs.
  • A systematic search revealed that human proteins with full-length microbial homologs are primarily involved in xenobiotic metabolism, particularly short-chain and aldo-keto reductases, while split homologs (where the microbial counterpart is divided among multiple genes) have roles in central metabolism.
  • The research identifies twelve specific drugs that gut microorganisms with split homologs may metabolize, emphasizing that understanding these relationships can help explain how gut bacteria influence drug breakdown and efficacy.
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