Factors which modulate the rates of skeletal muscle mass loss in non-small cell lung cancer patients: a pilot study.

Purpose: Advanced non-small cell lung cancer (NSCLC) is associated with weight loss which may reflect skeletal muscle mass (SMM) and/or total adipose tissue (TAT) depletion. This study aimed to describe changes in body composition (BC) parameters and to identify the factors unrelated to the tumor which modulate them.

Methods: SMM, TAT, and the proportion of SMM to SMM + TAT were assessed with computed tomography.

Patient-reported outcomes with lanreotide Autogel/Depot for carcinoid syndrome: An international observational study.

Background: Lanreotide Autogel/Depot effectively controls symptoms in patients with carcinoid syndrome associated with neuroendocrine tumours. Data on patient-reported outcomes are sparse.

Aim: To evaluate the effect of lanreotide on patient-reported outcomes (PROs) with carcinoid syndrome.

Oral bisphosphonates reduce the risk of clinical fractures in glucocorticoid-induced osteoporosis in clinical practice.

Unlabelled: This study aims to estimate bisphosphonate effectiveness by comparing fracture incidence over time on therapy in glucocorticoid-induced osteoporosis (GIO). From this observational study, alendronate and risedronate decreased clinical vertebral and nonvertebral fractures over time. The effectiveness of each bisphosphonate is consistent with their efficacies demonstrated on surrogate markers in randomized controlled trials (RCTs).