Bayesian calculation of methotrexate clearance after low dose intramuscular administration in patients with rheumatoid arthritis.

Objective: To determine a pharmacokinetic procedure (Bayesian method) for estimation of methotrexate (MTX) clearance, using only 2 blood samples, in outpatients with rheumatoid arthritis treated with low dose intramuscular (i.m.) MTX.

[Bacillary trochanteritis. Apropos of 30 cases].

Tuberculous trochanteritis is rare. The authors report 30 cases, 2/3 of which were seen in sanatoria. They occurred in four cases out of five in patients with long standing tuberculosis but were sometimes the presenting feature.