Publications by authors named "P Anjali"

Background: Epilepsy poses a significant global health challenge, particularly in regions with limited financial resources hindering access to treatment. Recent research highlights neuroinflammation, particularly involving cyclooxygenase-2 (COX-2) pathways, as a promising avenue for epilepsy management.

Methods: This study aimed to develop a Cyclooxygenase-2 inhibitor with potential anticonvulsant properties.

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Article Synopsis
  • Pharmacotherapy is a key treatment for allergic rhinitis, particularly topical steroids, but compliance can be a challenge due to daily usage requirements.
  • Submucosal inferior turbinoplasty was performed on 35 patients to evaluate its effectiveness as an alternative, showing significant improvements in various rhinitis symptoms and overall quality of life.
  • The study concluded that patients with allergic rhinitis and enlarged turbinates should consider turbinoplasty, with thorough counseling to understand the procedure's benefits and risks.*
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To document the clinical presentation, complications, management strategy and post-operative outcomes of extensive cholesteatomas. Cholesteatoma is a well demarcated cystic lesion derived from an abnormal growth of keratinizing squamous epithelium in the temporal bone. Cholesteatomas commonly involve the middle ear, epitympanum, mastoid antrum and air cells and can remain within these confines for a considerable period.

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Ossicular discontinuity is the most common cause of conductive hearing loss. The use of ossicular graft material in ossicular chain reconstruction significantly improves the result in hearing. This study was conducted to compare and analyze the outcome of ossicular reconstruction using allogenic septal spur cartilage and autologous cortical bone in terms of hearing results and graft uptake rates.

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This study has aimed to determine the anatomical site of labyrinthine fistula in patients of chronic suppurative otitis media at our centre. Labyrinthine fistulae (LF) are caused by abnormal communications between the inner ear and surrounding structures resulting in perilymph leakage and hearing loss. Labyrinthine fistula represents as erosive loss of the enchondral bone overlying the semicircular canals without loss of perilymph.

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