Publications by authors named "P Anikeeva"
Article Synopsis
- This text discusses how recording and modulation of neuronal activity can help in studying brain function in various health conditions and diseases.
- It highlights the use of advanced techniques, like optogenetics and chemical sensing, that enhance our understanding of brain chemistry and signaling in rodent models.
- The study showcases innovative fiber technology that integrates multiple recording methods, which allows researchers to simultaneously monitor and stimulate brain activity while also delivering drugs or genes, particularly in investigating the mesolimbic reward pathway in mice.
Article Synopsis
- Deep brain stimulation has greatly advanced the treatment of neurological and psychiatric disorders, and there's interest in finding less invasive alternatives.
- The study focuses on magnetoelectric nanodiscs (MENDs) that can convert magnetic fields into electric signals to modulate neurons remotely, showing effective results even below traditional stimulation thresholds.
- When injected into specific brain regions of mice, MENDs can control behaviors related to reward and movement, paving the way for new applications in neuroscience research and therapy.
We asked researchers from a range of disciplines across biology, engineering, and medicine to describe a current technological need. The goal is to provide a sample of the various technological gaps that exist and inspire future research projects.
View Article and Find Full Text PDFRecording and modulation of neuronal activity enables the study of brain function in health and disease. While translational neuroscience relies on electrical recording and modulation techniques, mechanistic studies in rodent models leverage genetic precision of optical methods, such as optogenetics and imaging of fluorescent indicators. In addition to electrical signal transduction, neurons produce and receive diverse chemical signals which motivate tools to probe and modulate neurochemistry.
View Article and Find Full Text PDFDeep-brain stimulation (DBS) with implanted electrodes revolutionized treatment of movement disorders and empowered neuroscience studies. Identifying less invasive alternatives to DBS may further extend its clinical and research applications. Nanomaterial-mediated transduction of magnetic fields into electric potentials offers an alternative to invasive DBS.
View Article and Find Full Text PDF