Publications by authors named "P Ambulkar"

Article Synopsis
  • Stroke is a medical emergency and is assessed using the NIH Stroke Scale; improving response times is crucial for effective thrombolysis and thrombectomy treatment.
  • A local stroke course at Great Western Hospital Swindon combined traditional methods and simulations to boost the skills and confidence of 24 medical professionals in managing stroke patients from November 2022 to July 2023.
  • The course showed significant improvements in understanding and confidence regarding thrombolysis (mean score increase of 3.75), thrombectomy (mean score increase of 3.4), NIHSS scoring (mean score increase of 4.33), and overall stroke assessment (mean score increase of 2.75), with nearly all participants rating it positively.
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Herbal extracts have evoked interest owing to the small number of terpenoids and phenolic compounds, which impart antimicrobial, antioxidant, and anti-inflammatory properties. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC) of four herbal extracts (lemon grass oil, basil oil, peppermint oil, and Obicure tea extract) against endodontic pathogens along with the MIC: MBC/MFC ratio were evaluated. The antimicrobial activity by detecting the MIC of three essential oils and tea extract was evaluated against eight common endodontic pathogens by the broth dilution method, while MBC was detected by subculturing onto blood agar from the first -three to five tubes from the MIC dilution tubes (showing no turbidity), which were plated on blood agar.

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Article Synopsis
  • * A case study of a 29-month-old girl showed severe developmental issues, including seizures, growth delays, and distinctive facial features, which were linked to abnormalities in her chromosome 21.
  • * Genetic analysis confirmed specific deletions in her DNA related to the ring chromosome formation, providing insights into the diverse expressions of symptoms associated with r(21) due to different cell line combinations.
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Protein supplements are extensively used for muscle building, weight loss, recovery from exercise, improving endurance & cardio-performance. Major challenge with protein supplement is undigested protein and impaired gut health which results in nausea, dehydration, diarrhea, constipation, indigestion, stomach pain, and decreased appetite. Several studies have linked plant protein with reduced metabolic syndrome incidence.

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Spermatogenesis is regulated by complex tissue specific gene expression in the testis to achieve normal male fertility. X-chromosome specific TATA binding protein (TBP)-associated factor 7L (hTAF7L) is one of the transcriptional regulator genes considered essential for spermatogenesis. The aim of this study was to evaluate the role of variants/mutations in the testis-specific hTAF7L gene in non-obstructive azoospermia and severe oligozoospermia male infertility.

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