Publications by authors named "P Amboiram"

Background: Human milk, especially the mother's own milk (MOM), is highly recommended for preterm babies considering its numerous benefits. Prioritising the use of exclusive MOM in enteral feeding plans is essential for maximising the health and development of preterm babies. This study evaluated the effect of early establishment of full enteral feed (FEF) with exclusive MOM on feeding rate and neonatal nutritional outcomes at discharge among preterm babies.

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Article Synopsis
  • Methaemoglobinaemia is a rare condition that can cause cyanosis, often linked to anaesthetic agents, but this case series highlights three instances related to acute gastroenteritis from formula feeds in newborns.
  • The infants presented with symptoms of hypoxia, metabolic acidosis, and diarrhea, which can complicate the usual diagnosis, emphasizing the need for awareness of this condition.
  • Rapid identification and treatment with methylene blue and fluid therapy were crucial, leading to successful recovery and discharge on exclusive breast feeds.
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Objectives: The objectives are to assess the effectiveness of a modified and adapted oral sensorimotor intervention (MA-OSMI) protocol for infants in India on the rate and performance of breastfeeding among preterm (PT) infants at discharge.

Design: Single-centre randomised control trial.

Setting: Level III B neonatal intensive care unit in a quaternary care hospital in South India.

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Article Synopsis
  • The study aimed to assess the effectiveness of endotoxin and endotoxin binding protein (EBP) in diagnosing late-onset neonatal sepsis (LOS) compared to C-reactive protein (CRP).
  • Conducted over two years in India, blood samples from neonates suspected of having LOS were analyzed for endotoxin, EBP, and CRP alongside blood cultures.
  • Results indicated that endotoxin and EBP had better specificity and comparable sensitivity to CRP, suggesting they can be useful biomarkers for diagnosing neonatal sepsis, reducing the reliance on time-consuming culture methods.
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