Isolation and antibacterial activity of anomanol B and other secondary metabolites from the stem bark of (Annonaceae).

A new Lanosta-7,9(11),22-trien-3,15,20-triol named Anomanol B together with five known compounds: manniindole , arborinine , polycarpol 8,9-dimethoxyphenanthridin-6(5)-one and 3-O--D-glucopyranosyl--sitosterol were isolated from the stem bark extract of by routine chromatography techniques. 8,9-dimethoxyphenanthridin-6(5)-one was reported from natural origin for the first time. The structures of the compounds were established by comprehensive elucidation of spectroscopic data and by comparison with literature data.

Inhibitory effects of 190 compounds against SARS-CoV-2 M protein: Molecular docking interactions.

COVID-19 has caused many deaths since the first outbreak in 2019. The burden on healthcare systems around the world has been reduced by the success of vaccines. However, population adherence and the occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants are still challenging tasks to be affronted.

The Antiplasmodial Potential of Medicinal Plants Used in the Cameroonian Pharmacopoeia: An Updated Systematic Review and Meta-Analysis.

Malaria is a real public health problem. It is the leading cause of morbidity and mortality in the world. Research in herbal medicine has so far shown that the use of plants against malaria is not to be neglected.

Chemical constituents of two Cameroonian medicinal plants: L. and Burm. f. (Malvaceae) and their antiplasmodial activity.

An extensive phytochemical investigation of the EtOH/HO (7:3) extracts of L. and Burm. f.