Publications by authors named "P Alifano"
Nanotechnology advancements have facilitated the development of eco-friendly strategies to combat bacterial infections caused by antibiotic-resistant pathogens. This study promotes a green method for the synthesis of silver nanoparticles (AgNPs) utilizing Eucalyptus globulus leaf extracts as an alternative to traditional colloidal AgNPs obtained through chemical synthesis, investigating their antibacterial efficacy against Pseudomonas aeruginosa and their impact on the expression of bacterial virulence factors (pyocyanin, pyoverdine, rhamnolipids). This work demonstrates that: i.
View Article and Find Full Text PDFis a self-pollinating species belonging to the Poaceae family characterized by a resistance to drought higher than that of corn. Sorghum ( L. Moench) has been grown for centuries as a food crop in tropical areas where it has an increasing importance, particularly as a cereal option for people with celiac disease.
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- Biofilm formation in hospitals and public places poses a significant risk for spreading infections, making antimicrobial coatings essential for prevention.
- The study introduces a spray coating technique utilizing copper oxide nanoparticles (CuO NPs) in a titanium dioxide (TiO) sol, where CuO NPs provide antimicrobial properties and TiO serves as the binder.
- Coated polypropylene substrates showed dual benefits: strong antibacterial effects and superhydrophobic properties, with higher CuO NP concentration resulting in increased antibacterial activity and water resistance.
Article Synopsis
- * Different bacteria, including Gram-negative types and their outer membrane vesicles (OMVs), can trigger pyroptosis in various cell types, which affects inflammation and barriers in our body, but more research is needed to fully understand these effects.
- * The review will delve into how pyroptosis pathways differ between harmful and harmless bacteria, while also examining experimental models and potential treatments that target these pathways to improve infection management.
Article Synopsis
- * A study using a reference strain and a knockout mutant showed that the HrpA/HrpB system is essential for disease progression, as the mutant exhibited impaired spreading and replication in the brain of infected mice.
- * Analysis of infected brain samples revealed that the mutant had reduced activation of key pyroptosis pathways and inflammatory markers, indicating that HrpA/HrpB is crucial for inducing pyroptosis during meningococcal infection.