Publications by authors named "P Alexopoulos"

Background: The role of primary healthcare is pivotal in the management of the surge of dementia prevalence particularly in low-resource areas. In this study, two telehealth-based memory clinics in primary healthcare operating within the frames of the INTegRated InterveNtion of pSychogerIatric Care (INTRINSIC) are presented.

Methods: The first clinic, which is led by a general practitioner, operates at a primary healthcare center in a semi-mountainous area and closely collaborates with the geriatric psychiatry outpatient clinic of the Patras University General Hospital via a telehealth medicine platform.

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  • Individuals with subjective cognitive decline (SCD) face a higher risk of developing dementia, and the GINGER initiative presents a multicomponent lifestyle intervention approach that includes exercise as a key component for prevention and management.
  • The exercise protocol designed for GINGER targets adults over 55 with SCD and involves a structured program of aerobic, strengthening, balance, and dual-task exercises, delivered three times a week, both in group sessions and at home.
  • The implementation of this exercise protocol was found to be feasible and reliable, showing good adherence and user satisfaction, along with notable improvements in physical health outcomes among participants.
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  • This study investigates the microstructure of the lamina cribrosa (LC) in nonhuman primates with glaucoma, focusing on how it differs in those with naturally occurring disease compared to controls.
  • Researchers used advanced imaging (OCT scans) to analyze the optic nerve head and select specific eyes based on retinal nerve fiber layer thickness (RNFL-T).
  • Key findings show that glaucoma-affected eyes had thinner RNFL-T and smaller pore diameters in the LC, indicating potential structural changes associated with the disease.
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  • Brain health is influenced by various factors, including physical health, environment, social connections, and access to healthcare, making it a complex area for decision-making.
  • Values-based practice (VBP) is introduced as a method to navigate conflicting interests among diverse stakeholders and promotes democratic participation in decision-making.
  • Successful implementation of VBP requires adherence to overarching values like mutual respect, autonomy, and equality, ensuring that all stakeholders feel valued throughout the process.
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