Probability of Remission of the Main Epileptic Syndromes in Childhood.

Aim: To determine the long-term probability of remission without antiepileptic treatment of common epileptic syndromes and of children without a specific syndromic diagnosis.

Patients And Methods: All children less than 14 years old with 2 or more unprovoked seizures seen at our hospital between June 1, 1994, and March 1, 2011 (n = 680), were included and prospectively followed up until August 15, 2020. Syndromic diagnosis was made retrospectively but blinded to subsequent evolution, employing the data available at 6 months after diagnosis and under predefined operational criteria.

[Frequency, semiology and prognosis of benign infantile epilepsy].

Introduction: Benign infantile epilepsy is an epileptic syndrome of infancy. Until now, only a small number of case-series have been published.

Aim: To study the frequency, semiology and prognosis of benign infantile epilepsy.

[Left hemiparesis as a sign of onset of vanishing white matter disease. Identification of a new mutation].

Vanishing white matter disease is a genetic disorder of autosomal recessive inheritance that affects the brain white matter There are various phenotypes that differ in severity and age at onset. Usually, it is characterized by ataxia, spasticity and a progressive motor decline with exacerbations triggered by fever and mild head traumas. The patient was a 2.

A study of drug-resistant childhood epilepsy testing the new ILAE criteria.

Purpose: To test the new ILAE definition of drug-resistant epilepsy in a cohort study.

Methods: All children younger than 14 with two or more unprovoked seizures observed at our hospital between 1994 and 2008 were included.

Results: Five hundred and eight patients were followed for an average of 90 months (range 24-168).

Response to sequential treatment schedules in childhood epilepsy: risk for development of refractory epilepsy.

Purpose: To investigate response to sequential treatment schedules and risk of development of refractory epilepsy in childhood.

Methods: All children younger than 14 years with two or more unprovoked seizures seen at our hospital between 1994 and 2004 were included and prospectively followed. "Seizure control" was defined as a 2-year seizure-free interval without further recurrences except those related to attempts of medication withdrawal and "refractory epilepsy" as failure of >2 drugs plus >1 seizure/month for > or =18 months.