Publications by authors named "P Afzelius"

Breast cancer usually metastasizes by haematogenous spread. This is a case report of a woman with unusual liver metastases from a recurrent invasive ductal carcinoma via a lymphatic route draining the outer part of the breast to the liver running parallelly with the right rectus abdominis muscle, depicted by preoperative sentinel node lymphoscintigraphy. Realizing this route of metastasis can impact survival, as it has a favourable prognosis compared with haematogenous metastasis, we want to draw attention to this.

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Background: [F]FDG and [C]methionine accumulate in lymph nodes draining -infected foci. The lymph nodes were characterized by weight, [C]methionine- and [F]FDG-positron emissions tomography (PET)/computed tomography (CT), and immunohistochemical (IHC)-staining.

Methods: 20 pigs inoculated with into the right femoral artery were PET/CT-scanned with [F]FDG, and nine of the pigs were additionally scanned with [C]methionine.

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The development of new and better radioactive tracers capable of detecting and characterizing osteomyelitis is an ongoing process, mainly because available tracers lack selectivity towards osteomyelitis. An integrated part of developing new tracers is the performance of in vivo tests using appropriate animal models. The available animal models for osteomyelitis are also far from ideal.

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Introduction: Radiotracers are widely used in medical imaging, using techniques of gamma-camera imaging (scintigraphy and SPECT) or positron emission tomography (PET). In bone marrow infection, there is no single routine test available that can detect infection with sufficiently high diagnostic accuracy. Here, we review radiotracers used for imaging of bone marrow infection, also known as osteomyelitis, with a focus on why these molecules are relevant for the task, based on their physiological uptake mechanisms.

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