Aging and MPTP Sensitivity Depend on Molecular and Ultrastructural Signatures of Astroglia and Microglia in Mice Substantia Nigra.

Both astroglia and microglia show region-specific distribution in CNS and often maladapt to age-associated alterations within their niche. Studies on autopsied substantia nigra (SN) of Parkinson's disease (PD) patients and experimental models propose gliosis as a trigger for neuronal loss. Epidemiological studies propose an ethnic bias in PD prevalence, since Caucasians are more susceptible than non-whites.

Material Extrusion Filament Width and Height Prediction via Design of Experiment and Machine Learning.

The dimensions of material extrusion 3D printing filaments play a pivotal role in determining processing resolution and efficiency and are influenced by processing parameters. This study focuses on four key process parameters, namely, nozzle diameter, nondimensional nozzle height, extrusion pressure, and printing speed. The design of experiment was carried out to determine the impact of various factors and interaction effects on filament width and height through variance analysis.

Land use change in rapidly developing economies-a case study on land use intensification and land fallowing in Kochi, Kerala, India.

The land use/land cover change is a local driver of environmental change having cascading impacts and implications at the global level, and therefore requires appreciable consideration when perceived from sustainability perspectives. Kerala, the southernmost state of India, has undergone a dramatic transition from a traditional agrarian economy to a modern thriving economy involving the irrational exploitation of natural resources, precisely, land and its components. The present study addresses how land is being changed along an urbanization gradient in the most agglomerative city in the state, Kochi, during the last one and half decades.

Seed enhancement technologies for sustainable dryland restoration: Coating and scarification.

High temperatures, soil salinity, a lack of available water, loose soils with reduced water holding, and low soil fertility are obstacles to restoration efforts in degraded drylands and desert ecosystems. Improved soil physical and chemical properties, seed germination and seedling recruitment, and plant growth are all proposed as outcomes of seed enhancement technologies (SETs). Seed priming, seed coating, and seed scarification are three SETs' methods for promoting seed germination and subsequent plant development under unfavorable environmental conditions.

A rapid assessment of stubble burning and air pollutants from satellite observations.

For the last several years, the air quality of India's capital Delhi and surrounding region (NCR) has been degrading to a very poor and severe category during the autumn season. In addition to the various sources of air pollutants within the NCR region, the stubble burning in Punjab and Haryana states contributes to the poor air quality in this region. The current study employs the Moderate Resolution Imaging Spectroradiometer (MODIS) active fire products and TROPOspheric Monitoring Instrument (TROPOMI) products on carbon monoxide (CO) and nitrogen dioxide (NO) concentrations for spatio-temporal assessment of stubble burning and associated emissions.