Publications by authors named "P A van Heusden"

Microbial research generates vast and complex data from diverse omics technologies, necessitating innovative analytical solutions. microGalaxy (Galaxy for Microbiology) addresses these needs with a user-friendly platform that integrates 220+ tool suites and 65+ curated workflows for microbial analyses, including taxonomic profiling, assembly, annotation, and functional analysis. Hosted on the main EU Galaxy server (microgalaxy.

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Article Synopsis
  • Microbial data sharing is crucial for effective public health research and pathogen analysis, evidenced by its importance during the SARS-CoV-2 pandemic.
  • There is currently a lack of universal guidelines for the secondary use of microbial data, despite general data-sharing principles existing.
  • The proposed PHA4GE Microbial Data-Sharing Accord outlines seven key principles to encourage responsible sharing and use of microbial data, aiming to enhance trust and prevent misuse in research.
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There is an ongoing explosion of scientific datasets being generated, brought on by recent technological advances in many areas of the natural sciences. As a result, the life sciences have become increasingly computational in nature, and bioinformatics has taken on a central role in research studies. However, basic computational skills, data analysis, and stewardship are still rarely taught in life science educational programs, resulting in a skills gap in many of the researchers tasked with analysing these big datasets.

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While plant genome analysis is gaining speed worldwide, few plant genomes have been sequenced and analyzed on the African continent. Yet, this information holds the potential to transform diverse industries as it unlocks medicinally and industrially relevant biosynthesis pathways for bioprospecting. Considering that South Africa is home to the highly diverse Cape Floristic Region, local establishment of methods for plant genome analysis is essential.

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