Xenographic lenticule implantation followed by riboflavin and UV treatment: A promising alternative for corneal ectasias management.

The cornea is the primary refracting surface of the eye, requiring precise curvature to ensure optimal vision. Any distortion in its shape may result in significant visual impairment. Corneal ectasias, such as keratoconus (KC), is characterized by gradual thinning and protrusion of the thinned area, due to biomechanical weakening of the tissue, leading to astigmatism and vision loss.

Digital solutions for migrant and refugee health: a framework for analysis and action.

Digital technologies can help support the health of migrants and refugees and facilitate research on their health issues. However, ethical concerns include security and confidentiality of information; informed consent; how to engage migrants in designing, implementing and researching digital tools; inequitable access to mobile devices and the internet; and access to health services for early intervention and follow-up. Digital technical solutions do not necessarily overcome problems that are political, social, or economic.

Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort.

Background: Cirrhosis has been pointed out as a clinical entity that leads to worse clinical prognosis in COVID-19 patients. However, this concept is controversial in the literature. We aimed to evaluate clinical outcomes by comparing patients with cirrhosis to those without cirrhosis in a Brazilian cohort.

Structural and functional insights into recombinant β-glucosidase from Thermothelomyces thermophilus: Cello-oligosaccharide hydrolysis and thermostability.

β-glucosidases (BGLs) are key enzymes in the depolymerization of cellulosic biomass, catalyzing the conversion of cello-oligosaccharides into glucose. This conversion is pivotal for enhancing the production of second-generation ethanol or other value-added products in biorefineries. However, the process is often cost-prohibitive due to the high enzyme loadings required.

Educational intervention in first aid for early childhood education professional: a quasi-experimental study.

Objective: To evaluate the effect of a first aid educational intervention on the aptitude, knowledge, and practices of professionals in early childhood education.

Method: Quasi-experimental study of the pre and post-test type carried out in the brazilian municipality of Três Lagoas, MS. It was developed in three stages: 1) application of an online instrument to assess aptitude, knowledge, and practices about situations that require first aid; 2) educational intervention, with four theoretical meetings online and a face-to-face meeting with practical training; 3) reapplying the questionnaire.