[Evaluation of the results of vestibuloplasty according to microhemodynamics and oxygenation in the mucous membrane of the alveolar ridge].

Objective: Evaluation of the effectiveness of vestibuloplasty according to microhemodynamics and oxygenation in the mucous membrane of the alveolar ridge.

Materials And Methods: To achieve this goal, a clinical and functional study was carried out in the mucous membrane of the alveolar ridge after vestibuloplasty in 80 patients (35 men and 45 women) aged from 18 to 65 years, average age 41.5±1.

[Learning curves in acquisition of experience for new technologies].

Objective: Analysis of national and foreign trials investigating accumulation of experience in innovative technologies using the learning curves.

Material And Methods. S: Earching for Russian-language manuscripts was carried out within the references of the articles and in the ELIBRARY database.

Atomic Structural Models of Fibrin Oligomers.

The space-filling fibrin network is a major part of clots and thrombi formed in blood. Fibrin polymerization starts when fibrinogen, a plasma protein, is proteolytically converted to fibrin, which self-assembles to form double-stranded protofibrils. When reaching a critical length, these intermediate species aggregate laterally to transform into fibers arranged into branched fibrin network.

Structural Basis of Interfacial Flexibility in Fibrin Oligomers.

Fibrin is a filamentous network made in blood to stem bleeding; it forms when fibrinogen is converted into fibrin monomers that self-associate into oligomers and then to polymers. To gather structural insights into fibrin formation and properties, we combined high-resolution atomic force microscopy of fibrin(ogen) oligomers and molecular modeling of crystal structures of fibrin(ogen) and its fragments. We provided a structural basis for the intermolecular flexibility of single-stranded fibrin(ogen) oligomers and identified a hinge region at the D:D inter-monomer junction.

Cell effects of xenon in vitro under hypothermal conditions.

The effects of Xe on cell viability and redox balance in the culture of Wistar rat thymocytes were studied in vitro during 24-h storage under hypothermic conditions. The results indicate that after bubbling of cell suspensions (5 x 10(6) cell/ml, 4 ml medium), the weight of Xe in flasks was 15-43 mg, whereas in cell-free medium no weight increment due to gas accumulation in the system was detected. The content of Xe in cell suspension slightly decreased over 24-h culturing at ambient temperature (by 10% of initial level).