Publications by authors named "P A Vriesendorp"
Background: Conduction disturbances are common after transcatheter aortic valve implantation (TAVI) and frequently require permanent pacemaker implantation (PPI). Data regarding its impact on mortality and morbidity are conflicting. This study aims to assess the impact of PPI before or within 30 days after TAVI on mortality and health-related Quality of Life (QoL) during the first year after TAVI.
View Article and Find Full Text PDFBackground: Concomitant coronary artery disease (CAD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI). The optimal treatment strategy for CAD is a topic of debate. An initial conservative strategy for CAD in patients undergoing TAVI may be favorable as multiple studies have failed to show an evident beneficial effect of percutaneous coronary intervention (PCI) on mortality after TAVI.
View Article and Find Full Text PDFArticle Synopsis
- Major or life-threatening bleeding and stroke are complications that can occur after transcatheter aortic valve implantation (TAVI), impacting both mortality and quality of life (QoL).
- Major bleeding increases the risk of death significantly, while minor bleeding does not affect mortality; however, both types of bleeding and stroke lead to lower mental QoL scores.
- The study highlights that monitoring these complications is essential, as they correlate with poorer mental well-being in patients during the first year post-TAVI.
Article Synopsis
- * In a trial with 858 patients, results showed no significant difference in major complications between those who continued anticoagulation (16.5% experienced primary outcomes) and those who interrupted it (14.8%).
- * Continuation of anticoagulation led to higher incidences of major bleeding (31.1% vs. 21.3%), suggesting that interrupting anticoagulation is safer in this patient population undergoing TAVI.
Modeling creatine-kinase MB concentrations following coronary artery bypass grafting.
J Thorac Cardiovasc Surg
August 2024
Article Synopsis
- The study focuses on improving the detection of periprocedural myocardial infarction (PMI) after coronary artery bypass grafting (CABG) by analyzing the changes in cardiac biomarker CK-MB over time.
- It involved 635 patients with 1589 CK-MB measurements, where the majority showed no signs of PMI, pinpointing key factors like patient sex and surgical specifics that influence CK-MB levels.
- A web-based application was developed to model CK-MB kinetics; the model achieved notable diagnostic accuracy, indicating its potential for wider use in monitoring and validating other cardiac biomarkers.