Special article: T. H. Seldon (1905-1991).

Dr. Seldon was Editor of Anesthesia & Analgesia from 1954 to 1977. We examined how he led the effort to transform this journal into a clinically relevant and vital publication for the specialty.

Anesthetic management of patients with Huntington disease.

Background: Huntington disease (HD) is a rare autosomal dominant disease with symptoms of chorea, dystonia, incoordination, cognitive decline, and behavioral difficulties. Abnormal responses to anesthesia have been reported in case reports and raised concerns regarding the safety of anesthesia in this patient population.

Methods: We performed a computerized search of the Mayo Clinic medical records database searching for patients with HD who underwent general anesthesia.

Regional uptake of meal fatty acids in humans.

Two protocols were performed to study meal fatty acid metabolism. In protocol 1, 14 patients scheduled for elective intra-abdominal surgery (11 undergoing bariatric surgery for severe obesity) consumed a meal containing [3H]triolein in the evening before surgery. This allowed us to measure adipose tissue lipid specific activity (SA) in mesenteric and omental, deep and superficial abdominal subcutaneous adipose tissue.